Pregnancy HistoryDuring pregnancy, any reported exposures or maternal conditions would be reasonable to refer to a genetics service – especially those known to be teratogens
E.g. accutane, seizure medications, lithium, coumadin, “street drugs”, high fevers, viral infections, maternal diabetes, etc.
Preconception counseling should always include a discussion of folic acid
Thought to decrease the risk of neural tube defects by 50-70%
0.4 mg is recommend for all women
4.0 mg is recommended for women at increased risk