introduction to white blood cells

38 slides
1.57 MB
495 views

Similar Presentations

Presentation Transcript

1

INTRODUCTION TO WHITE BLOOD CELLS developed by Liz Fracalanza Tina Goodyear Hugh B. Fackrell Dept of Biological Sciences University of Windsor Windsor, ON Canada

2

OBJECTIVESTo examine the formed elements of blood To define the structure and function of the cellular elements To differentiate between the various blood cells

3

IntroductionBlood may be separated into a clear fluid composed of either serum or plasma and formed elements which contain cells and cell fragments Next

4

Formed Elements of BloodLeucocytes (white blood cells) Erythrocytes (red blood cells) Thrombocytes (platelets)

5

Frequency of W.B.C in Human Blood WBC % number/mm3 neutrophil 54-69 2700-6900 lymphocyte 25-33 1250-3300 monocyte 3-7 150-700 eosinophil 1-3 50-300 basophil 0-0.75 0-75 Next

6

Structure and function of the cellular elements

7

NEUTROPHILSCharacteristics Ultrastructure Functions Distribution

8

Neutrophil CharacteristicsDiameter :9 -16um Cytoplasm :pink Nucleus :2-5 lobes,dark blue Life-span :5 days Granules :present(not visible) Next

9

Next

10

Neutrophil FunctionsRespond chemotactically to various stimuli (complement, lymphokines and bacterial membrane components) Phagocytosis of foreign particles and microbes NEXT

11

Distribution of NeutrophilsApproximately one-half of the neutrophils found in the body are attached to the endothelial lining of the blood vessels, poised to cross the blood vessel wall and attack an infection Next

12

EOSINOPHILSLight microscopy Ultra structure Functions

13

Eosinophil CharacteristicsDiameter : 10 - 15 um Cytoplasm : pink-grey Nucleus : purple, bi-lobed Life-span : 1 day Granules : Many, large, bright orange/red NEXT

14

Eosinophil Ultrastructure

15

Eosinophil FunctionChemotactic response to complement, antibodies and histamine Active against parasites by phagocytosis and secretion of granular contents next

16

BASOPHILSCharacteristics Ultrastructure Functions

17

Basophil CharacteristicsDiameter :10 -15 um Cytoplasm :basophilic (blue) Nucleus :not usually seen may be lobed Granules :many, large, dark purple, covers nucleus next

18

Basophil EM

19

Basophil Ultrastructure

20

Basophil Functions Secretes substances during an allergic reaction Secretes large amounts of heparin, which is an anticoagulant Secretes histamine, which participates in constriction of the blood vessels, bronchioles and intestines next

21

LARGE LYMPHOCYTES

22

Large Lymphocyte CharacteristicsDiameter :10 - 18 um Cytoplasm :sky-blue - deep-blue may be vacuolated Nucleus :mono-nuclear, dense chromatin, dark blue Granules : may be few Nucleus/cytoplasm ratio is 1:1

23

SMALL LYMPHOCYTES

24

Small Lymphocyte CharacteristicsDiameter : 6-10 um Cytoplasm : sky-blue - dark-blue Nucleus : round, oval, blue Life-span : about 10 years Granules : none - fewNucleus/cytoplasm ratio is 4:1

25

Lymphocyte Ultrastructure

26

Lymphocyte Function Lymphocytes can behave as one of three major cell types: 1. T lymphocytes 2. B lymphocytes 3. Natural Killer cells

Browse More Presentations

Last Updated: 8th March 2018

Recommended PPTs